Adadin yawan abin da ya faru a tsakanin yara masu shekaru 6 zuwa shekaru 10 shine 2.7 a cikin mutum-watanni 100 a cikin yankin IRS da 6.8 a cikin kowane watanni 100 na mutum a cikin yankin sarrafawa. Duk da haka, babu wani gagarumin bambanci game da cutar zazzabin cizon sauro a tsakanin wuraren biyu a cikin watanni biyu na farko (Yuli-Agusta) da kuma bayan damina (December-Fabrairu) (duba Hoto na 4).
Kaplan-Meier masu lankwasa na rayuwa ga yara masu shekaru 1 zuwa shekaru 10 a cikin yankin binciken bayan watanni 8 na biyo baya.
Wannan binciken ya kwatanta yawaitar cutar zazzabin cizon sauro da abin da ya faru a gundumomi biyu ta hanyar amfani da dabarun magance cutar zazzabin cizon sauro don tantance ƙarin tasirin IRS. An tattara bayanai a cikin gundumomi biyu ta hanyar bincike-biyu na sassan biyu da binciken binciken shari'a na watanni 9 a asibitocin lafiya. Sakamako daga bincike-bincike a farkon da ƙarshen lokacin watsa cutar zazzabin cizon sauro ya nuna cewa cutar zazzabin cizon sauro ta yi ƙasa sosai a gundumar IRS (LLTID+IRS) fiye da gundumar kulawa (LLTIN kawai). Tunda gundumomi biyu suna kwatankwacinsu dangane da cutar zazzabin cizon sauro da kuma sa baki, ana iya bayyana wannan bambancin ta ƙarin ƙimar IRS a gundumar IRS. A zahiri, duka gidan yanar gizo na kwari da kuma IRS an san su don rage nauyin zazzabin cizon sauro yayin amfani da su kadai. Don haka, yawancin binciken [7, 21, 23, 24, 25] sun yi hasashen cewa haɗuwarsu za ta haifar da raguwar nauyin zazzabin cizon sauro fiye da ɗaya kaɗai. Duk da IRS, Plasmodium parasitaemia yana ƙaruwa daga farkon zuwa ƙarshen lokacin damina a wuraren da ake yada cutar zazzabin cizon sauro, kuma ana sa ran wannan yanayin zai yi girma a ƙarshen lokacin damina. Koyaya, haɓakar yankin IRS (53.0%) ya ragu sosai fiye da na yankin sarrafawa (220.0%). Shekaru tara na kamfen na IRS a jere babu shakka sun taimaka wajen rage ko ma danne kololuwar watsa kwayar cuta a cikin wuraren IRS. Bugu da ƙari, babu wani bambanci a cikin ma'anar gametophyte tsakanin yankunan biyu a farkon. A ƙarshen lokacin damina, ya kasance mafi girma a cikin wurin sarrafawa (11.5%) fiye da a cikin rukunin IRS (3.2%). Wannan abin lura a wani bangare yana bayyana mafi ƙarancin kamuwa da cutar zazzabin cizon sauro a cikin yankin IRS, tunda ma'anar gametocyte shine yuwuwar tushen kamuwa da cutar sauro wanda ke haifar da watsa cutar malaria.
Sakamakon binciken da aka yi na logistics ya nuna ainihin hadarin da ke tattare da kamuwa da cutar zazzabin cizon sauro a cikin yankin da aka sarrafa kuma ya nuna cewa haɗin tsakanin zazzabi da parasitemia ya wuce kima kuma anemia wani abu ne mai rudani.
Kamar yadda yake tare da parasitaemia, kamuwa da cutar zazzabin cizon sauro a tsakanin yara masu shekaru 0-10 ya ragu sosai a cikin IRS fiye da wuraren sarrafawa. An lura da kololuwar watsawa na gargajiya a bangarorin biyu, amma sun kasance ƙasa da ƙasa sosai a cikin IRS fiye da yankin sarrafawa (Hoto 3). A haƙiƙa, yayin da magungunan kashe qwari ke ɗaukar kusan shekaru 3 a cikin LLINs, suna dawwama har zuwa watanni 6 a cikin IRS. Don haka, ana gudanar da kamfen na IRS kowace shekara don rufe kololuwar watsawa. Kamar yadda Kaplan-Meier curves na rayuwa ya nuna (Hoto na 4), yaran da ke zaune a yankunan IRS ba su da ƙarancin cutar zazzabin cizon sauro fiye da waɗanda ke cikin wuraren kulawa. Wannan ya yi daidai da sauran nazarin da suka ba da rahoton raguwar raguwar kamuwa da cutar zazzabin cizon sauro lokacin da aka faɗaɗa IRS tare da wasu ayyukan. Koyaya, ƙayyadaddun lokacin kariya daga ragowar tasirin IRS yana nuna cewa wannan dabarar na iya buƙatar haɓakawa ta amfani da magungunan kwari masu dorewa ko haɓaka mitar aikace-aikacen shekara-shekara.
Bambance-bambance a cikin yaɗuwar anemia tsakanin IRS da wuraren sarrafawa, tsakanin ƙungiyoyin shekaru daban-daban da tsakanin mahalarta tare da ba tare da zazzaɓi ba na iya zama alama mai kyau kai tsaye na dabarun da aka yi amfani da su.
Wannan binciken ya nuna cewa pirimiphos-methyl IRS na iya rage yawan kamuwa da cutar zazzabin cizon sauro a yara 'yan kasa da shekaru 10 a yankin Koulikoro mai jure wa pyrethroid, kuma yaran da ke zaune a yankunan IRS sun fi kamuwa da cutar zazzabin cizon sauro kuma su kasance marasa cutar malaria. ya dade a yankin. Nazarin ya nuna cewa pirimiphos-methyl shine maganin kwari mai dacewa don maganin zazzabin cizon sauro a yankunan da juriya na pyrethroid ya zama ruwan dare.
Lokacin aikawa: Dec-09-2024