Chlormequat wani abu nemai kula da girman shukawanda amfaninsa a amfanin gonakin hatsi ke ƙaruwa a Arewacin Amurka. Nazarin Toxicology ya nuna cewa fallasa ga chlormequat na iya rage haihuwa da kuma haifar da lahani ga tayin da ke tasowa a allurai ƙasa da adadin da hukumomin kula da lafiya suka amince da shi na yau da kullun. A nan, mun bayar da rahoton kasancewar chlormequat a cikin samfuran fitsari da aka tattara daga al'ummar Amurka, tare da ƙimar ganowa na 69%, 74%, da 90% a cikin samfuran da aka tattara a cikin 2017, 2018–2022, da 2023, bi da bi. Daga 2017 zuwa 2022, an gano ƙarancin yawan chlormequat a cikin samfuran, kuma daga 2023, yawan chlormequat a cikin samfuran ya ƙaru sosai. Mun kuma lura cewa an sami chlormequat akai-akai a cikin samfuran oat. Waɗannan sakamakon da bayanan guba na chlormequat suna tayar da damuwa game da matakan fallasa a halin yanzu kuma suna kira da a ƙara yin gwaje-gwaje masu zurfi game da guba, sa ido kan abinci, da nazarin cututtuka don tantance tasirin fallasa chlormequat akan lafiyar ɗan adam.
Wannan binciken ya ba da rahoton gano chlormequat, wani sinadari na noma wanda ke da guba ga ci gaba da haihuwa, a cikin al'ummar Amurka da kuma a cikin wadatar abinci ta Amurka. Duk da cewa an sami irin wannan matakin sinadari a cikin samfuran fitsari daga 2017 zuwa 2022, an sami ƙaruwar matakan a cikin samfurin 2023. Wannan aikin ya nuna buƙatar sa ido sosai kan chlormequat a cikin samfuran abinci da na ɗan adam a Amurka, da kuma toxicology da toxicology. Nazarin cututtuka na chlormequat, kamar yadda wannan sinadari gurɓatacce ne mai tasowa tare da rubuce-rubucen illolin lafiya a ƙananan allurai a cikin nazarin dabbobi.
Chlormequat sinadari ne na noma da aka fara rijista a Amurka a shekarar 1962 a matsayin mai kula da ci gaban shuka. Duk da cewa a halin yanzu an yarda da amfani da shi ne kawai a kan tsire-tsire masu ado a Amurka, wani hukunci da Hukumar Kare Muhalli ta Amurka (EPA) ta yanke a shekarar 2018 ya ba da damar shigo da kayayyakin abinci (galibi hatsi) da aka yi wa magani da chlormequat [1]. A Tarayyar Turai, Burtaniya da Kanada, an amince da amfani da chlormequat a kan amfanin gona, galibi alkama, hatsi da sha'ir. Chlormequat na iya rage tsayin tushe, ta haka ne rage yiwuwar amfanin gona ya karkace, wanda hakan ke sa girbi ya yi wahala. A Burtaniya da Tarayyar Turai, chlormequat galibi shine mafi yawan ragowar magungunan kashe kwari da aka gano a cikin hatsi da hatsi, kamar yadda aka rubuta a cikin nazarin sa ido na dogon lokaci [2, 3].
Duk da cewa an amince da amfani da chlormequat don amfanin gona a sassan Turai da Arewacin Amurka, yana nuna kaddarorin guba bisa ga binciken dabbobi na tarihi da aka buga kwanan nan. An fara bayyana tasirin fallasa chlormequat akan gubar haihuwa da haihuwa a farkon shekarun 1980 ta hanyar manoman alade na Denmark waɗanda suka lura da raguwar aikin haihuwa a cikin aladu da aka noma a kan hatsin da aka yi wa chlormequat. Daga baya an duba waɗannan abubuwan lura a cikin gwaje-gwajen dakin gwaje-gwaje da aka sarrafa a cikin aladu da beraye, inda aladu mata da aka yi wa chlormequat magani suka nuna matsala a cikin zagayowar estrous da haɗuwa idan aka kwatanta da dabbobin da aka yi wa abinci ba tare da chlormequat ba. Bugu da ƙari, beraye maza da aka fallasa ga chlormequat ta hanyar abinci ko ruwan sha yayin haɓakawa sun nuna raguwar ikon takin maniyyi a cikin vitro. Binciken gubar haihuwa na baya-bayan nan na chlormequat ya nuna cewa fallasa beraye ga chlormequat a lokacin lokutan ci gaba masu mahimmanci, gami da ciki da farkon rayuwa, ya haifar da jinkirin balaga, raguwar motsi na maniyyi, raguwar nauyin gabobin haihuwa na maza, da raguwar matakan testosterone. Nazarin gubar ci gaba kuma ya nuna cewa fallasa ga chlormequat yayin daukar ciki na iya haifar da ci gaban tayi da rashin daidaituwar metabolism. Wasu bincike ba su gano wani tasiri na chlormequat akan aikin haihuwa a cikin beraye mata da aladu maza ba, kuma babu wani bincike da ya biyo baya da ya gano tasirin chlormequat akan haihuwa na beraye maza da aka fallasa ga chlormequat yayin ci gaba da rayuwar bayan haihuwa. Bayanan da ba su dace ba game da chlormequat a cikin wallafe-wallafen guba na iya zama saboda bambance-bambance a cikin allurai da ma'auni na gwaji, da kuma zaɓin samfuran halittu da jinsi na dabbobin gwaji. Saboda haka, ana buƙatar ƙarin bincike.
Duk da cewa binciken da aka yi kwanan nan kan guba ya nuna tasirin chlormequat akan ci gaba, haifuwa da tsarin endocrine, hanyoyin da waɗannan tasirin guba ke faruwa ba a san su ba. Wasu bincike sun nuna cewa chlormequat bazai yi aiki ta hanyar ingantattun hanyoyin sinadarai masu lalata endocrine ba, gami da masu karɓar estrogen ko androgen, kuma baya canza ayyukan aromatase. Wasu shaidu sun nuna cewa chlormequat na iya haifar da illa ta hanyar canza yanayin steroid da haifar da damuwa na endoplasmic reticulum.
Duk da cewa chlormequat yana nan a ko'ina a cikin abincin Turai, adadin nazarin biomonitoring da ke tantance yadda ɗan adam ke shan chlormequat ƙarami ne. Chlormequat yana da ɗan gajeren rabin rai a jiki, kimanin awanni 2-3, kuma a cikin binciken da ya shafi masu sa kai na mutane, yawancin allurai na gwaji an cire su daga jiki cikin awanni 24. A cikin samfuran jama'a gabaɗaya daga Burtaniya da Sweden, an gano chlormequat a cikin fitsari na kusan kashi 100% na mahalarta binciken a cikin mafi yawan mitoci da yawa fiye da sauran magungunan kashe kwari kamar chlorpyrifos, pyrethroids, thiabendazole da mancozeb metabolites. Nazarin da aka yi a cikin aladu ya nuna cewa ana iya samun chlormequat a cikin jini kuma ana iya canza shi zuwa madara, amma ba a yi nazarin waɗannan matrices a cikin mutane ko wasu samfuran dabbobi na gwaji ba, kodayake kasancewarsa a cikin jini da madara na iya dangantawa da cutarwa daga sinadarai. Akwai mahimman tasirin fallasa yayin daukar ciki da jarirai.
A watan Afrilun 2018, Hukumar Kare Muhalli ta Amurka ta sanar da matakin da ya dace na jure wa abinci ga chlormequat a cikin hatsi, alkama, sha'ir, da wasu kayayyakin dabbobi da aka shigo da su daga waje, wanda hakan ya ba da damar shigo da chlormequat cikin wadatar abinci ta Amurka. Daga baya an ƙara yawan hatsin da aka yarda da shi a shekarar 2020. Don kwatanta tasirin waɗannan shawarwarin kan faruwar da yaɗuwar chlormequat a cikin yawan manya na Amurka, wannan binciken gwaji ya auna adadin chlormequat a cikin fitsarin mutane daga yankuna uku na Amurka daga 2017 zuwa 2023 da kuma a 2022. da kuma yawan chlormequat na kayayyakin oat da alkama da aka saya a Amurka a 2023.
An yi amfani da samfuran da aka tattara a yankuna uku na ƙasa tsakanin 2017 da 2023 don auna matakin fitsari na chlormequat a cikin mazauna Amurka. An tattara samfuran fitsari ashirin da ɗaya daga mata masu juna biyu waɗanda aka tantance waɗanda suka yarda a lokacin haihuwa bisa ga yarjejeniyar da Hukumar Bita ta Cibiya (IRB) ta amince da ita a 2017 daga Jami'ar Likitanci ta South Carolina (MUSC, Charleston, SC, Amurka). An adana samfuran a zafin jiki na 4°C har zuwa awanni 4, sannan aka raba su aka daskare su a -80°C. An sayi samfuran fitsari manya ashirin da biyar daga Lee Biosolutions, Inc (Maryland Heights, MO, Amurka) a watan Nuwamba 2022, wanda ke wakiltar samfurin guda ɗaya da aka tattara daga Oktoba 2017 zuwa Satumba 2022, kuma an tattara su daga masu sa kai (maza 13 da mata 12) a kan aro ga tarin Maryland Heights, Missouri. An adana samfuran a -20°C nan da nan bayan an tattara su. Bugu da ƙari, an sayi samfuran fitsari guda 50 da aka tattara daga masu sa kai na Florida (maza 25, mata 25) a watan Yunin 2023 daga BioIVT, LLC (Westbury, NY, Amurka). An adana samfuran a zafin 4°C har sai an tattara dukkan samfuran, sannan aka raba su aka daskare su a -20°C. Kamfanin mai samar da kayayyaki ya sami amincewar IRB da ake buƙata don sarrafa samfuran ɗan adam da kuma izinin tattara samfuran. Ba a bayar da bayanan sirri a cikin kowane samfurin da aka gwada ba. An aika duk samfuran daskararre don yin bincike. Ana iya samun cikakkun bayanai game da samfurin a cikin Teburin Bayani na Tallafi na S1.
An tantance adadin chlormequat a cikin samfuran fitsari na ɗan adam ta hanyar LC-MS/MS a dakin gwaje-gwajen bincike na HSE (Buxton, UK) bisa ga hanyar da Lindh et al suka buga. An ɗan gyara shi kaɗan a shekarar 2011. A takaice, an shirya samfuran ta hanyar haɗa μl 200 na fitsarin da ba a tace ba da 1.8 ml na 0.01 M ammonium acetate wanda ke ɗauke da ma'aunin ciki. Daga nan aka cire samfurin ta amfani da ginshiƙin HCX-Q, aka fara sanya shi da methanol, sannan aka wanke shi da 0.01 M ammonium acetate, sannan aka cire shi da 0.01 M ammonium acetate, sannan aka cire shi da 1% formic acid a cikin methanol. Daga nan aka ɗora samfuran a kan ginshiƙin C18 LC (Synergi 4 µ Hydro-RP 150 × 2 mm; Phenomenex, UK) sannan aka raba su ta amfani da yanayin motsi na isocratic wanda ya ƙunshi 0.1% formic acid:methanol 80:20 a ƙimar kwarara 0.2 ml/min. Lindh et al. 2011 sun bayyana canjin amsawar da aka zaɓa ta hanyar amfani da mass spectrometry. Iyakar ganowa ita ce 0.1 μg/L kamar yadda aka ruwaito a wasu nazarin.
Ana bayyana yawan sinadarin chlormequat na fitsari a matsayin μmol chlormequat/mol creatinine kuma ana canza shi zuwa μg chlormequat/g creatinine kamar yadda aka ruwaito a cikin binciken da suka gabata (a ninka da 1.08).
Anresco Laboratories, LLC ta gwada samfuran abinci na hatsi (na gargajiya 25 da na halitta 8) da alkama (na gargajiya 9) don chlormequat (San Francisco, CA, Amurka). An yi nazarin samfuran tare da gyare-gyare bisa ga hanyoyin da aka buga [19]. LOD/LOQ don samfuran hatsi a cikin 2022 da kuma ga dukkan samfuran alkama da hatsi a cikin 2023 an saita su a 10/100 ppb da 3/40 ppb, bi da bi. Cikakken bayanin samfurin za a iya samu a cikin Teburin Bayani na Tallafi S2.
An rarraba yawan sinadarin chlormequat na fitsari ta hanyar wurin da aka ware da kuma shekarar da aka tattara shi, ban da samfuran da aka tattara a shekarar 2017 daga Maryland Heights, Missouri, waɗanda aka haɗa su da wasu samfuran 2017 daga Charleston, South Carolina. An yi amfani da samfuran da ke ƙasa da iyakar gano chlormequat a matsayin kashi-kashi da aka raba ta tushen murabba'i na 2. Ba a saba rarraba bayanai ba, don haka an yi amfani da gwajin Kruskal-Wallis mara mizani da gwajin kwatantawa da yawa na Dunn don kwatanta matsakaici tsakanin ƙungiyoyi. An yi duk lissafin a cikin GraphPad Prism (Boston, MA).
An gano Chlormequat a cikin samfuran fitsari 77 cikin 96, wanda ke wakiltar kashi 80% na dukkan samfuran fitsari. Idan aka kwatanta da 2017 da 2018–2022, an gano samfuran 2023 akai-akai: an gwada samfuran 16 cikin 23 (ko 69%) da samfuran 17 cikin 23 (ko 74%), bi da bi, kuma an gwada samfuran 45 cikin 50 (watau 90%) (Tebur 1). Kafin 2023, yawan chlormequat da aka gano a cikin ƙungiyoyin biyu daidai yake, yayin da yawan chlormequat da aka gano a cikin samfuran 2023 ya fi girma fiye da na samfuran shekarun da suka gabata (Hoto na 1A,B). Yawan abubuwan da za a iya ganowa na samfuran 2017, 2018–2022, da 2023 sun kasance daga 0.22 zuwa 5.4, 0.11 zuwa 4.3, da kuma 0.27 zuwa 52.8 micrograms na chlormequat a kowace gram na creatinine, bi da bi. Matsakaicin ƙimar duk samfuran a cikin 2017, 2018–2022, da 2023 sune 0.46, 0.30, da 1.4, bi da bi. Waɗannan bayanai sun nuna cewa fallasa na iya ci gaba idan aka yi la'akari da ɗan gajeren rabin rayuwar chlormequat a jiki, tare da ƙarancin matakan fallasa tsakanin 2017 da 2022 da kuma mafi girman matakan fallasa a cikin 2023.
An gabatar da yawan sinadarin chlormequat na kowane samfurin fitsari a matsayin maki ɗaya tare da sanduna a sama da matsakaicin sandunan kuskure kuma suna wakiltar kuskuren +/- na yau da kullun. Ana bayyana yawan sinadarin chlormequat na fitsari a cikin mcg na chlormequat a kowace gram na creatinine akan sikelin layi da sikelin logarithmic. An yi amfani da nazarin bambance-bambancen Kruskal-Wallis mara mizani tare da gwajin kwatantawa da yawa na Dunn don gwada mahimmancin ƙididdiga.
Samfuran abinci da aka saya a Amurka a shekarun 2022 da 2023 sun nuna matakan chlormequat da za a iya ganowa a cikin dukkan kayayyakin hatsi na gargajiya guda biyu banda biyu daga cikin kayayyakin hatsi na gargajiya guda 25, tare da yawan da ba a iya ganowa ba har zuwa 291 μg/kg, wanda ke nuna cewa chlormequat yana cikin hatsi. Yaɗuwar cin ganyayyaki yana da yawa. Samfuran da aka tattara a shekarar 2022 da 2023 suna da matsakaicin matsayi iri ɗaya: 90 µg/kg da 114 µg/kg, bi da bi. Samfuri ɗaya kawai daga cikin kayayyakin hatsi guda takwas na halitta yana da adadin chlormequat da za a iya ganowa na 17 µg/kg. Mun kuma lura da ƙarancin yawan chlormequat a cikin samfuran alkama guda biyu daga cikin samfuran alkama tara da aka gwada: 3.5 da 12.6 μg/kg, bi da bi.
Wannan shine rahoto na farko game da auna sinadarin chlormequat na fitsari a cikin manya da ke zaune a Amurka da kuma a cikin al'ummomin da ke wajen Burtaniya da Sweden. Yanayin sa ido kan magungunan kashe kwari a tsakanin matasa sama da 1,000 a Sweden ya sami kashi 100% na gano chlormequat daga 2000 zuwa 2017. Matsakaicin yawan da aka samu a shekarar 2017 shine microgram 0.86 na chlormequat a kowace gram na creatinine kuma da alama ya ragu akan lokaci, tare da matsakaicin matakin mafi girma shine 2.77 a 2009. A Burtaniya, sa ido kan kwayoyin halitta ya gano matsakaicin yawan chlormequat mafi girma na microgram 15.1 na chlormequat a kowace gram na creatinine tsakanin 2011 da 2012, kodayake an tattara waɗannan samfuran daga mutanen da ke zaune a yankunan noma. babu bambanci a cikin fallasa. Matsalar feshi[15]. Bincikenmu game da samfurin Amurka daga 2017 zuwa 2022 ya gano ƙananan matakan matsakaici idan aka kwatanta da nazarce-nazarcen da suka gabata a Turai, yayin da a cikin 2023 matakan matsakaici na samfurin sun yi daidai da samfurin Sweden amma sun yi ƙasa da samfurin Burtaniya.
Waɗannan bambance-bambancen da ake samu tsakanin yankuna da lokutan lokaci na iya nuna bambance-bambance a ayyukan noma da matsayin ƙa'idojin chlormequat, wanda a ƙarshe ke tasiri ga matakan chlormequat a cikin kayayyakin abinci. Misali, yawan chlormequat a cikin samfuran fitsari ya fi girma sosai a cikin 2023 idan aka kwatanta da shekarun da suka gabata, wanda zai iya nuna canje-canje da suka shafi ayyukan ƙa'idojin EPA da suka shafi chlormequat (gami da iyakokin abincin chlormequat a cikin 2018). Kayayyakin abinci na Amurka nan gaba kaɗan. Ƙara ƙa'idodin amfani da oat nan da 2020. Waɗannan ayyukan suna ba da damar shigo da kayayyakin noma da aka yi wa magani da chlormequat, misali, daga Kanada. Ana iya bayyana jinkirin da ke tsakanin canje-canjen ƙa'idojin EPA da yawan chlormequat da aka samu a cikin samfuran fitsari a cikin 2023 ta hanyoyi da dama, kamar jinkiri a cikin ɗaukar ayyukan noma waɗanda ke amfani da chlormequat, jinkiri da kamfanonin Amurka ke yi wajen yin shawarwari kan yarjejeniyoyin ciniki, da kuma mutane masu zaman kansu. suna fuskantar jinkiri wajen siyan oat saboda raguwar tsoffin kayayyaki da/ko saboda tsawon rayuwar kayayyakin oat.
Domin tantance ko yawan da aka lura a cikin samfuran fitsari na Amurka yana nuna yuwuwar kamuwa da chlormequat a cikin abinci, mun auna chlormequat a cikin kayayyakin oat da alkama da aka saya a Amurka a cikin 2022 da 2023. Kayayyakin oat suna ɗauke da chlormequat sau da yawa fiye da kayayyakin alkama, kuma adadin chlormequat a cikin samfuran oat daban-daban ya bambanta, tare da matsakaicin matakin 104 ppb, wataƙila saboda wadatar da aka samu daga Amurka da Kanada, wanda zai iya nuna bambance-bambancen amfani ko rashin amfani tsakanin samfuran da aka samar daga hatsi da aka yi wa magani da chlormequat. Sabanin haka, a cikin samfuran abinci na Burtaniya, chlormequat ya fi yawa a cikin samfuran alkama kamar burodi, tare da gano chlormequat a cikin 90% na samfuran da aka tattara a Burtaniya tsakanin Yuli da Satumba 2022. Matsakaicin yawan shine 60 ppb. Hakazalika, an gano chlormequat a cikin kashi 82% na samfuran hatsi na Burtaniya a matsakaicin yawan ppb 1650, wanda ya fi sau 15 fiye da na samfuran Amurka, wanda hakan na iya bayyana yawan yawan fitsari da aka gani a samfuran Burtaniya.
Sakamakon bincikenmu na biomonitor ya nuna cewa fallasa ga chlormequat ya faru kafin 2018, kodayake ba a tabbatar da juriya ga abinci ga chlormequat ba. Duk da cewa ba a sarrafa chlormequat a cikin abinci a Amurka ba, kuma babu wani bayanai na tarihi game da yawan chlormequat a cikin abincin da ake sayarwa a Amurka, idan aka yi la'akari da ɗan gajeren lokacin chlormequat, muna zargin cewa wannan fallasar na iya zama abincin da ake ci. Bugu da ƙari, abubuwan da suka fara haifar da choline a cikin kayayyakin alkama da foda ƙwai suna samar da chlormequat a yanayin zafi mai yawa, kamar waɗanda ake amfani da su a sarrafa abinci da masana'antu, wanda ke haifar da yawan chlormequat daga 5 zuwa 40 ng/g. Sakamakon gwajin abinci namu ya nuna cewa wasu samfura, gami da samfurin oat na halitta, sun ƙunshi chlormequat a matakan kama da waɗanda aka ruwaito a cikin binciken chlormequat na halitta, yayin da wasu samfura da yawa sun ƙunshi manyan matakan chlormequat. Don haka, matakan da muka lura a cikin fitsari har zuwa 2023 wataƙila sun faru ne saboda fallasa ga chlormequat na abinci da aka samar yayin sarrafa abinci da masana'antu. Matakan da aka lura a shekarar 2023 na iya faruwa ne sakamakon cin abinci mai dauke da sinadarin chlormequat da aka samar ba zato ba tsammani da kuma kayayyakin da aka shigo da su daga waje da aka yi wa magani da sinadarin chlormequat a fannin noma. Bambancin kamuwa da sinadarin chlormequat a tsakanin samfuranmu na iya faruwa ne saboda yanayin wurin da muke, yanayin abinci daban-daban, ko kuma kamuwa da sinadarin chlormequat a wurin aiki idan aka yi amfani da shi a gidajen kore da wuraren renon yara.
Bincikenmu ya nuna cewa ana buƙatar manyan samfuran girma da kuma samfuran abinci daban-daban da aka yi wa magani da chlormequat don tantance cikakken tushen abinci na chlormequat ga mutanen da ba su da isasshen fallasa. Nazarin da za a yi nan gaba, ciki har da nazarin samfuran fitsari da abinci na tarihi, tambayoyin abinci da na aiki, ci gaba da sa ido kan chlormequat a cikin abinci na gargajiya da na halitta a Amurka, da samfuran kula da halittu, za su taimaka wajen fayyace abubuwan da suka fi haifar da fallasa chlormequat a cikin al'ummar Amurka.
Har yanzu ba a tantance yiwuwar ƙaruwar sinadarin chlormequat a cikin fitsari da samfuran abinci a Amurka a cikin shekaru masu zuwa ba. A Amurka, a halin yanzu ana ba da izinin amfani da chlormequat ne kawai a cikin kayayyakin hatsi da alkama da aka shigo da su daga ƙasashen waje, amma Hukumar Kare Muhalli a halin yanzu tana la'akari da amfani da shi a fannin noma a cikin amfanin gona na cikin gida waɗanda ba na halitta ba. Idan aka amince da irin wannan amfani a cikin gida tare da yaduwar aikin gona na chlormequat a ƙasashen waje da kuma a cikin gida, matakan chlormequat a cikin hatsi, alkama, da sauran kayayyakin hatsi na iya ci gaba da ƙaruwa, wanda ke haifar da ƙaruwar yawan chlormequat. Jimlar yawan jama'ar Amurka.
Yawan chlormequat a cikin fitsari a yanzu a cikin wannan da sauran bincike ya nuna cewa an fallasa samfurin da aka bayar ga masu ba da gudummawar chlormequat a matakan da suka kasance ƙasa da adadin da Hukumar Kare Muhalli ta Amurka ta buga (RfD) (0.05 mg/kg nauyin jiki a kowace rana), don haka ana iya yarda da shi. Yawan shan kowace rana ya yi ƙasa da ƙimar shan da Hukumar Tsaron Abinci ta Turai (ADI) ta buga (0.04 mg/kg nauyin jiki/rana). Duk da haka, mun lura cewa binciken da aka buga game da toxicology na chlormequat ya nuna cewa sake kimanta waɗannan matakan aminci na iya zama dole. Misali, beraye da aladu da aka fallasa ga allurai ƙasa da RfD da ADI na yanzu (0.024 da 0.0023 mg/kg nauyin jiki/rana, bi da bi) sun nuna raguwar haihuwa. A wani binciken toxicology, fallasa a lokacin daukar ciki ga allurai daidai da matakin mummunan tasirin da ba a lura da shi ba (NOAEL) na 5 mg/kg (wanda aka yi amfani da shi don ƙididdige adadin da Hukumar Kare Muhalli ta Amurka ta yi amfani da shi) ya haifar da canje-canje a cikin girman tayin da metabolism, da kuma canje-canje a cikin tsarin jiki. Berayen jarirai. Bugu da ƙari, ƙa'idodin ƙa'idoji ba sa la'akari da mummunan tasirin gaurayen sinadarai waɗanda za su iya shafar tsarin haihuwa, waɗanda aka nuna suna da tasirin ƙari ko haɗin gwiwa a allurai ƙasa da fallasa ga sinadarai daban-daban, suna haifar da matsaloli masu yuwuwar lafiyar haihuwa. Damuwa game da sakamakon da ke tattare da matakan fallasa a yanzu, musamman ga waɗanda ke da matakan fallasa mafi girma a cikin yawan jama'a a Turai da Amurka.
Wannan bincike na gwaji kan sabbin sinadarai da aka fallasa a Amurka ya nuna cewa chlormequat yana nan a cikin abincin Amurka, musamman a cikin kayayyakin oat, da kuma a cikin mafi yawan samfuran fitsari da aka gano da aka tattara daga kusan mutane 100 a Amurka, yana nuna ci gaba da fallasa chlormequat. Bugu da ƙari, yanayin da ke cikin waɗannan bayanai ya nuna cewa matakan fallasa sun ƙaru kuma suna iya ci gaba da ƙaruwa a nan gaba. Ganin damuwar guba da ke tattare da fallasa chlormequat a cikin nazarin dabbobi, da kuma yaduwar yawan jama'a ga chlormequat a ƙasashen Turai (kuma yanzu wataƙila a Amurka), tare da nazarin cututtuka da dabbobi, akwai buƙatar gaggawa Kula da chlormequat a cikin abinci da mutane Chlormequat. Yana da mahimmanci a fahimci yuwuwar haɗarin lafiya na wannan sinadari na noma a matakan fallasa muhalli, musamman a lokacin daukar ciki.
Lokacin Saƙo: Yuni-04-2024