Chlormequat shine mai kula da haɓakar shuka wanda amfaninsa a cikin amfanin gona na hatsi yana ƙaruwa a Arewacin Amurka.Nazarin toxicology sun nuna cewa fallasa ga chlormequat na iya rage haihuwa da kuma haifar da lahani ga tayin da ke tasowa a cikin allurai da ke ƙasa da adadin da aka yarda da shi na yau da kullun da hukumomin da suka tsara suka kafa.Anan, mun ba da rahoton kasancewar chlormequat a cikin samfuran fitsari da aka tattara daga yawan jama'ar Amurka, tare da ƙimar ganowa na 69%, 74%, da 90% a samfuran da aka tattara a cikin 2017, 2018-2022, da 2023, bi da bi.Daga 2017 zuwa 2022, an gano ƙananan ƙwayoyin chlormequat a cikin samfurori, kuma daga 2023, ƙididdigar chlormequat a cikin samfurori ya karu sosai.Mun kuma lura cewa ana samun chlormequat akai-akai a cikin kayayyakin hatsi.Waɗannan sakamakon da bayanan guba na chlormequat suna tayar da damuwa game da matakan fallasa na yanzu kuma suna kira don ƙarin gwajin guba mai yawa, sa ido kan abinci, da nazarin cututtukan cututtuka don tantance tasirin bayyanar chlormequat akan lafiyar ɗan adam.
Wannan binciken ya ba da rahoton gano farko na chlormequat, agrochemical tare da haɓakar haɓakawa da haɓakar haihuwa, a cikin yawan jama'ar Amurka da wadatar abinci na Amurka.Yayin da aka sami irin wannan matakan sinadarai a cikin samfuran fitsari daga 2017 zuwa 2022, an sami matakan haɓaka sosai a cikin samfurin 2023.Wannan aikin yana ba da haske game da buƙatar faɗaɗa kulawar chlormequat a cikin abinci da samfuran ɗan adam a cikin Amurka, da kuma toxicology da toxicology.Nazarin cututtukan cututtuka na chlormequat, saboda wannan sinadari mai gurɓatacce ne mai tasowa tare da rubutattun illolin kiwon lafiya a ƙananan allurai a cikin nazarin dabbobi.
Chlormequat wani sinadari ne na noma da aka fara rajista a Amurka a cikin 1962 a matsayin mai kula da haɓaka tsiro.Kodayake a halin yanzu an ba da izinin amfani da tsire-tsire na ado a cikin Amurka, shawarar Hukumar Kare Muhalli ta Amurka (EPA) ta 2018 ta ba da izinin shigo da kayan abinci (mafi yawan hatsi) da aka yi da chlormequat.A cikin EU, Burtaniya da Kanada, an amince da chlormequat don amfani da amfanin gona na abinci, galibi alkama, hatsi da sha'ir.Chlormequat na iya rage tsayin dashen, ta yadda zai rage yuwuwar amfanin gona ya karkace, yin girbi mai wahala.A cikin Burtaniya da EU, chlormequat gabaɗaya ita ce mafi yawan ragowar magungunan kashe qwari a cikin hatsi da hatsi, kamar yadda aka rubuta a cikin binciken sa ido na dogon lokaci.
Kodayake chlormequat an amince da amfani da shi akan amfanin gona a sassa na Turai da Arewacin Amurka, yana nuna kaddarorin toxicological dangane da tarihi da binciken dabba na gwaji da aka buga kwanan nan.An fara bayyana tasirin bayyanar chlormequat akan gubar haihuwa da haihuwa a farkon shekarun 1980 ta manoma aladun Danish waɗanda suka lura da raguwar aikin haifuwa a cikin aladu da aka taso akan hatsin da aka yi wa chlormequat.Daga baya an bincika waɗannan abubuwan lura a cikin gwaje-gwajen dakin gwaje-gwaje masu sarrafawa a cikin aladu da beraye, inda aladu mata ke ciyar da hatsin da aka yi wa chlormequat suna nuna damuwa a cikin hawan keke da mating idan aka kwatanta da dabbobi masu kulawa da ke ciyar da abinci ba tare da chlormequat ba.Bugu da ƙari, ƙananan berayen da aka fallasa ga chlormequat ta hanyar abinci ko ruwan sha yayin haɓakawa sun nuna raguwar ikon takin maniyyi a cikin vitro.Nazarin chlormequat na baya-bayan nan game da guba na haifuwa ya nuna cewa bayyanar berayen zuwa chlormequat a lokacin lokacin haɓakawa masu mahimmanci, gami da ciki da farkon rayuwa, ya haifar da jinkirin balaga, raguwar motsin maniyyi, rage nauyin gabobin haihuwa na maza, da rage matakan testosterone.Har ila yau, nazarin haɓakar haɓakawa ya nuna cewa bayyanar chlormequat a lokacin daukar ciki na iya haifar da girma tayin da rashin daidaituwa na rayuwa.Sauran nazarin ba su sami wani tasiri na chlormequat akan aikin haifuwa a cikin mice mata da aladu maza ba, kuma babu wani binciken da ya biyo baya ya gano tasirin chlormequat akan haifuwar mice da aka fallasa ga chlormequat yayin ci gaba da rayuwar haihuwa.Bayanan daidaitattun bayanai akan chlormequat a cikin wallafe-wallafen toxicological na iya zama saboda bambance-bambance a cikin allurai na gwaji da ma'auni, da kuma zaɓin kwayoyin halitta da jima'i na dabbobin gwaji.Saboda haka, ƙarin bincike yana da garantin.
Ko da yake kwanan nan binciken toxicological ya nuna ci gaba, haifuwa da kuma endocrin sakamakon chlormequat, hanyoyin da waɗannan abubuwan da ke faruwa ba su da tabbas.Wasu nazarin sun nuna cewa chlormequat bazai aiki ta hanyar ingantattun hanyoyin sinadarai masu lalata endocrine, gami da isrogen ko masu karɓar isrogen, kuma baya canza ayyukan aromatase.Wasu shaidun sun nuna cewa chlormequat na iya haifar da sakamako masu illa ta hanyar canza biosynthesis na steroid da haifar da damuwa na endoplasmic reticulum.
Kodayake chlormequat yana kasancewa a ko'ina a cikin abinci na Turai gama gari, adadin binciken nazarin halittu da ke tantance bayyanar ɗan adam ga chlormequat kaɗan ne.Chlormequat yana da ɗan gajeren rabin rayuwa a cikin jiki, kimanin sa'o'i 2-3, kuma a cikin binciken da ya shafi masu aikin sa kai na ɗan adam, yawancin gwajin gwaji an share su daga jiki a cikin sa'o'i 24 [14].A cikin samfuran yawan jama'a daga Burtaniya da Sweden, an gano chlormequat a cikin fitsari kusan 100% na mahalarta binciken a mafi girman mitoci da yawa fiye da sauran magungunan kashe qwari kamar chlorpyrifos, pyrethroids, thiabendazole da mancozeb metabolites.Binciken da aka yi a aladu ya nuna cewa ana iya gano chlormequat a cikin ruwan magani kuma a canza shi zuwa madara, amma ba a yi nazarin waɗannan matrices a cikin mutane ko wasu nau'in dabba na gwaji ba, kodayake ana iya samun alamun chlormequat a cikin jini da madara da ke da alaƙa da cutar da haihuwa.abu.Akwai mahimman tasirin bayyanarwa a lokacin daukar ciki da jarirai .
A cikin Afrilu 2018, Hukumar Kare Muhalli ta Amurka ta ba da sanarwar yarda da matakan jurewar abinci ga chlormequat a cikin hatsi da aka shigo da su, alkama, sha'ir, da wasu kayayyakin dabbobi, suna ba da damar shigo da chlormequat cikin wadatar abinci na Amurka.Abin da ke cikin oat da aka yarda ya karu daga baya a cikin 2020. Don kwatanta tasirin waɗannan yanke shawara kan faruwa da yawaitar chlormequat a cikin yawan jama'ar Amurka, wannan binciken matukin jirgi ya auna adadin chlormequat a cikin fitsarin mutane daga yankuna uku na Amurka daga 2017. zuwa 2023 da sake a cikin 2022. da abun ciki na chlormequat na hatsi da kayayyakin alkama da aka saya a Amurka a cikin 2023.
Samfuran da aka tattara a yankuna uku tsakanin 2017 da 2023 an yi amfani da su don auna matakan fitsari na chlormequat a mazauna Amurka.An tattara samfuran fitsari 21 daga waɗanda aka bayyana mata masu juna biyu waɗanda suka yarda a lokacin haihuwa bisa ga ka'idar 2017 Institutional Review Board (IRB) -da aka amince da ita daga Jami'ar Medical University of South Carolina (MUSC, Charleston, SC, Amurka).An adana samfurori a 4 ° C har zuwa sa'o'i 4, sa'an nan kuma a daskare a -80 ° C.An sayi samfuran fitsarin manya 25 daga Lee Biosolutions, Inc (Maryland Heights, MO, Amurka) a cikin Nuwamba 2022, wakiltar samfurin guda ɗaya da aka tattara daga Oktoba 2017 zuwa Satumba 2022, kuma an karɓa daga masu sa kai (maza 13 da mata 12).) a kan lamuni zuwa tarin Maryland Heights, Missouri.An adana samfurori a -20 ° C nan da nan bayan tattarawa.Bugu da kari, samfuran fitsari 50 da aka tattara daga masu sa kai na Florida (maza 25, mata 25) a watan Yuni 2023 an siyo su daga BioIVT, LLC (Westbury, NY, Amurka).An adana samfurori a zazzabi na 4 ° C har sai an tattara dukkan samfurori sannan a daskare a -20 ° C.Kamfanin mai kaya ya sami amincewar IRB masu dacewa don aiwatar da samfuran ɗan adam da kuma yarda da tarin samfurin.Ba a bayar da bayanan sirri ba a cikin kowane samfurin da aka gwada.An aika duk samfuran a daskarewa don bincike.Ana iya samun cikakken bayanin samfurin a Teburin Tallafawa S1.
Ƙididdigar chlormequat a cikin samfuran fitsari na ɗan adam an ƙaddara ta LC-MS/MS a HSE Research Laboratory (Buxton, UK) bisa ga hanyar da Lindh et al ya buga.An gyara dan kadan a cikin 2011. A taƙaice, an shirya samfurori ta hanyar haɗuwa da 200 μl na fitsari mara kyau tare da 1.8 ml na 0.01 M ammonium acetate dauke da daidaitattun ciki.Sa'an nan kuma an fitar da samfurin ta hanyar amfani da ginshiƙin HCX-Q, wanda aka sanya shi da farko tare da methanol, sa'an nan kuma tare da 0.01 M ammonium acetate, an wanke shi da 0.01 M ammonium acetate, kuma ya tashi tare da 1% formic acid a cikin methanol.Sannan an ɗora samfuran a kan ginshiƙi na C18 LC (Synergi 4 µ Hydro-RP 150 × 2 mm; Phenomenex, UK) kuma an raba su ta amfani da tsarin wayar hannu na isocratic wanda ya ƙunshi 0.1% formic acid: methanol 80: 20 a ƙimar kwarara 0.2.ml/min.Lindh et al ne suka bayyana canjin martanin da aka zaɓa ta hanyar yawan gani.2011. Ƙimar ganowa shine 0.1 μg / L kamar yadda aka ruwaito a cikin wasu nazarin.
Matsakaicin chlormequat na fitsari ana bayyana su azaman μmol chlormequat/mol creatinine kuma an canza su zuwa μg chlormequat/g creatinine kamar yadda aka ruwaito a cikin binciken da suka gabata ( ninka ta 1.08).
Anresco Laboratories, LLC sun gwada samfuran abinci na hatsi (na al'ada 25 da 8 Organic) da alkama (na al'ada 9) don chlormequat (San Francisco, CA, Amurka).An yi nazarin samfurori tare da gyare-gyare bisa ga hanyoyin da aka buga.LOD/LOQ don samfuran hatsi a cikin 2022 kuma ga duk samfuran alkama da hatsi a cikin 2023 an saita su a 10/100 ppb da 3/40 ppb, bi da bi.Ana iya samun cikakken bayanin samfurin a Teburin Tallafawa S2.
Matsakaicin chlormequat na fitsari an haɗa su ta wurin yanki da kuma shekarar tarawa, ban da samfurori biyu da aka tattara a cikin 2017 daga Maryland Heights, Missouri, waɗanda aka haɗa tare da wasu samfuran 2017 daga Charleston, South Carolina.Samfuran da ke ƙasa da iyakar gano chlormequat an bi da su azaman gano kashi kashi da aka raba ta tushen murabba'in 2. Ba a rarraba bayanai akai-akai, don haka gwajin Kruskal-Wallis marasa daidaituwa da gwajin kwatancen Dunn da yawa an yi amfani da su don kwatanta tsaka-tsaki tsakanin ƙungiyoyi.An yi duk lissafin a GraphPad Prism (Boston, MA).
An gano Chlormequat a cikin 77 na samfuran fitsari 96, wanda ke wakiltar 80% na duk samfuran fitsari.Idan aka kwatanta da 2017 da 2018-2022, 2023 samfurori an gano akai-akai: 16 daga 23 samfurori (ko 69%) da 17 daga 23 samfurori (ko 74%), bi da bi, da 45 daga 50 samfurori (watau 90%) .) an gwada su.Kafin 2023, ƙididdigar chlormequat da aka gano a cikin ƙungiyoyin biyu sun yi daidai, yayin da adadin chlormequat da aka gano a cikin samfuran 2023 ya fi girma fiye da samfuran daga shekarun baya (Hoto 1A, B).Abubuwan da ake iya ganowa don samfuran 2017, 2018-2022, da 2023 sune 0.22 zuwa 5.4, 0.11 zuwa 4.3, da 0.27 zuwa 52.8 micrograms na chlormequat a kowace gram na creatinine, bi da bi.Matsakaicin matsakaici don duk samfuran a cikin 2017, 2018-2022, da 2023 sune 0.46, 0.30, da 1.4, bi da bi.Waɗannan bayanan sun ba da shawarar cewa fallasa na iya ci gaba da ba da ɗan gajeren rabin rayuwar chlormequat a cikin jiki, tare da ƙananan matakan fallasa tsakanin 2017 da 2022 da matakan fallasa mafi girma a cikin 2023.
Matsakaicin chlormequat na kowane samfurin fitsari ana gabatar dashi azaman aya ɗaya tare da sanduna sama da ma'ana da sandunan kuskure waɗanda ke wakiltar kuskure +/- daidaitaccen kuskure.Matsalolin chlormequat na fitsari ana bayyana su a cikin mcg na chlormequat kowace gram na creatinine akan sikelin layi (A) da ma'aunin logarithmic (B).Binciken Kruskal-Wallis marasa daidaituwa na bambance-bambance tare da gwajin kwatancen Dunn da yawa an yi amfani da shi don gwada mahimmancin ƙididdiga.
Samfuran abinci da aka saya a Amurka a cikin 2022 da 2023 sun nuna matakan gano chlormequat a cikin duka biyu daga cikin samfuran hatsi na gargajiya 25, tare da adadin da ba a iya ganowa zuwa 291 μg/kg, yana nuna chlormequat a cikin hatsi.Yawan cin ganyayyaki ya yi yawa.Samfuran da aka tattara a cikin 2022 da 2023 suna da matsakaicin matsakaicin matakan: 90 μg/kg da 114 µg/kg, bi da bi.Samfurin guda ɗaya ne kawai na samfuran hatsi guda takwas yana da abun ciki na chlormequat wanda ake iya ganowa na 17 μg/kg.Mun kuma lura da ƙananan adadin chlormequat a cikin biyu daga cikin samfuran alkama tara da aka gwada: 3.5 da 12.6 μg/kg, bi da bi (Table 2).
Wannan shi ne rahoton farko na ma'aunin chlormequat na fitsari a cikin manya da ke zaune a Amurka da kuma a cikin jama'ar da ke wajen Burtaniya da Sweden.Hanyoyin sarrafa magungunan kashe qwari a tsakanin matasa fiye da 1,000 a Sweden sun rubuta adadin gano 100% na chlormequat daga 2000 zuwa 2017. Matsakaicin maida hankali a cikin 2017 shine 0.86 micrograms na chlormequat a kowace gram na creatinine kuma ya bayyana ya ragu akan lokaci, tare da matsakaicin matsakaici. 2.77 a cikin 2009 [16].A cikin Burtaniya, binciken biomonitoring ya sami matsakaicin matsakaicin matsakaicin chlormequat na 15.1 micrograms na chlormequat kowace gram na creatinine tsakanin 2011 da 2012, kodayake an tattara waɗannan samfuran daga mutanen da ke zaune a yankunan noma.babu bambanci a cikin fallasa.Lamarin fesa[15].Nazarin mu na samfurin Amurka daga 2017 zuwa 2022 ya sami ƙananan matakan tsaka-tsaki idan aka kwatanta da binciken da aka yi a baya a Turai, yayin da a cikin 2023 matakan tsaka-tsakin samfurori sun kasance daidai da samfurin Sweden amma ƙasa da samfurin Birtaniya (Table 1).
Waɗannan bambance-bambance a cikin fallasa tsakanin yankuna da wuraren lokaci na iya nuna bambance-bambance a cikin ayyukan noma da matsayi na chlormequat, wanda a ƙarshe yana tasiri matakan chlormequat a cikin samfuran abinci.Misali, adadin chlormequat a cikin samfuran fitsari ya kasance mafi girma a cikin 2023 idan aka kwatanta da shekarun da suka gabata, wanda zai iya nuna canje-canjen da suka danganci ayyukan EPA da suka shafi chlormequat (gami da iyakokin abinci na chlormequat a cikin 2018).Kayan abinci na Amurka nan gaba kadan.Haɓaka ka'idojin amfani da hatsi nan da 2020. Waɗannan ayyukan suna ba da damar shigo da siyar da kayayyakin aikin gona da aka yi da chlormequat, misali, daga Kanada.Lalacewar da ke tsakanin sauye-sauyen tsarin EPA da yawan adadin chlormequat da aka samu a cikin samfuran fitsari a cikin 2023 ana iya bayyana shi ta yanayi da yawa, kamar jinkirin karɓar ayyukan noma da ke amfani da chlormequat, jinkirin da kamfanonin Amurka suka yi wajen kulla yarjejeniyar kasuwanci, sannan kuma sun fuskanci jinkiri a cikin siyan oat saboda raguwar tsoffin kayan ƙirƙira da/ko tsawon rayuwar samfuran hatsi.
Don sanin ko adadin da aka gani a samfuran fitsarin Amurka yana nuna yuwuwar bayyanarwar abinci ga chlormequat, mun auna chlormequat a cikin kayan oat da alkama da aka saya a Amurka a cikin 2022 da 2023. Kayayyakin hatsi sun ƙunshi chlormequat sau da yawa fiye da samfuran alkama, da adadin chlormequat a ciki. samfuran hatsi daban-daban sun bambanta, tare da matsakaicin matakin 104 ppb, mai yiwuwa saboda samarwa daga Amurka da Kanada, wanda zai iya nuna bambance-bambancen amfani ko rashin amfani.tsakanin samfuran da aka samar daga hatsi da aka yi da chlormequat.Sabanin haka, a cikin samfuran abinci na Burtaniya, chlormequat ya fi yawa a cikin samfuran alkama kamar burodi, tare da chlormequat da aka gano a cikin 90% na samfuran da aka tattara a Burtaniya tsakanin Yuli da Satumba 2022. Matsakaicin matsakaici shine 60 ppb.Hakanan, an gano chlormequat a cikin kashi 82% na samfuran hatsin oat na Burtaniya a matsakaicin maida hankali na 1650 ppb, fiye da sau 15 sama da samfuran Amurka, wanda zai iya yin bayanin mafi girman adadin fitsari da aka lura a samfuran Burtaniya.
Sakamakon binciken mu na nazarin halittu ya nuna cewa fallasa ga chlormequat ya faru kafin 2018, kodayake ba a tabbatar da juriyar abinci ga chlormequat ba.Kodayake chlormequat ba a sarrafa shi a cikin abinci a cikin Amurka, kuma babu wani bayanan tarihi kan yawan chlormequat a cikin abincin da ake sayarwa a Amurka, idan aka ba da ɗan gajeren rabin rayuwar chlormequat, muna zargin cewa wannan fallasa na iya zama abin da ake ci.Bugu da ƙari, precursors choline a cikin samfuran alkama da foda kwai a zahiri suna samar da chlormequat a yanayin zafi mai zafi, kamar waɗanda ake amfani da su wajen sarrafa abinci da masana'anta, wanda ke haifar da adadin chlormequat daga 5 zuwa 40 ng/g. Sakamakon gwajin abincinmu ya nuna cewa wasu samfuran, gami da samfurin oat na halitta, ya ƙunshi chlormequat a matakan kama da waɗanda aka ruwaito a cikin nazarin chlormequat da ke faruwa a zahiri, yayin da sauran samfuran da yawa sun ƙunshi matakan chlormequat mafi girma.Don haka, matakan da muka lura a cikin fitsari ta hanyar 2023 mai yiwuwa ne saboda bayyanar abinci ga chlormequat da aka samar yayin sarrafa abinci da masana'anta.Matakan da aka lura a cikin 2023 mai yuwuwa ne saboda fallasa abinci ga chlormequat da aka samar ba da dadewa ba da samfuran da aka shigo da su da chlormequat a cikin aikin gona.Bambance-bambance a cikin bayyanar chlormequat a tsakanin samfuran mu na iya kasancewa saboda wurin yanki, nau'ikan abinci daban-daban, ko bayyanar da sana'a ga chlormequat lokacin amfani da su a cikin gidajen kore da gandun daji.
Bincikenmu ya nuna cewa ana buƙatar manyan nau'ikan samfura da samfuran nau'ikan abincin da aka yi wa chlormequat don cikakken kimanta hanyoyin abinci na chlormequat a cikin mutane masu ƙarancin fallasa.Nazarin gaba ciki har da nazarin fitsari na tarihi da samfuran abinci, tambayoyin abinci da na sana'a, ci gaba da sa ido kan chlormequat a cikin abinci na al'ada da na halitta a cikin Amurka, da samfuran kula da halittu zasu taimaka haɓaka abubuwan gama gari na bayyanar chlormequat a cikin yawan jama'ar Amurka.
Yiwuwar ƙara matakan chlormequat a cikin fitsari da samfuran abinci a Amurka a cikin shekaru masu zuwa ya rage a tantance.A cikin Amurka, a halin yanzu ana ba da izinin chlormequat a cikin hatsi da kayayyakin alkama da ake shigowa da su, amma Hukumar Kare Muhalli a halin yanzu tana la'akari da amfani da aikin noma a cikin amfanin gona da ba na asali ba.Idan an yarda da irin wannan amfanin cikin gida tare da aikin noma na chlormequat a waje da cikin gida, matakan chlormequat a cikin hatsi, alkama, da sauran kayan hatsi na iya ci gaba da haɓaka, wanda zai haifar da matakan chlormequat mafi girma.Jimlar yawan jama'ar Amurka.
Ƙididdigar fitsari na chlormequat na yanzu a cikin wannan da sauran binciken sun nuna cewa masu ba da gudummawar samfurin kowane mutum an fallasa su ga chlormequat a matakan da ke ƙasa da adadin da aka buga na Hukumar Kare Muhalli ta Amurka (RfD) (0.05 mg / kg nauyin jiki kowace rana), don haka an yarda da su. .Abincin yau da kullun yana da umarni da yawa na girma ƙasa da ƙimar abincin da Hukumar Kare Abinci ta Turai (ADI) ta buga (0.04 mg/kg nauyin jiki/rana).Koyaya, mun lura cewa binciken binciken toxicology da aka buga na chlormequat yana ba da shawarar cewa sake kimanta waɗannan ƙofofin aminci na iya zama dole.Misali, mice da aladu da aka fallasa zuwa allurai da ke ƙasa da RfD na yanzu da ADI (0.024 da 0.0023 mg / kg nauyin jiki / rana, bi da bi) sun nuna raguwar haihuwa.A cikin wani binciken toxicology, fallasa yayin daukar ciki zuwa allurai daidai da matakin sakamako mara kyau (NOAEL) na 5 mg/kg (wanda aka yi amfani da shi don ƙididdige adadin ƙididdigar Hukumar Kare Muhalli ta Amurka) ya haifar da canje-canje a cikin girma tayi da metabolism, haka nan. kamar yadda canje-canje a cikin tsarin jiki.Mice masu haihuwa .Bugu da ƙari, ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun abubuwa ba su haifar da mummunan tasirin gaurayawan sinadarai ba wanda zai iya rinjayar tsarin haifuwa, wanda aka nuna yana da ƙari ko tasirin synergistic a allurai ƙasa da fallasa ga sinadarai na mutum, haifar da matsalolin kiwon lafiya.Damuwa game da sakamakon da ke da alaƙa da matakan fallasa na yanzu, musamman ga waɗanda ke da matakan fallasa mafi girma a cikin yawan jama'a a Turai da Amurka.
Wannan bincike na matukin jirgi na sabbin sinadarai a cikin Amurka ya nuna cewa chlormequat yana cikin abincin Amurka, musamman a cikin kayayyakin hatsi, da kuma mafi yawan samfuran fitsari da aka gano da aka tattara daga kusan mutane 100 a Amurka, wanda ke nuna ci gaba da kamuwa da chlormequat.Bugu da ƙari, abubuwan da ke cikin waɗannan bayanan sun nuna cewa matakan fallasa sun karu kuma suna iya ci gaba da karuwa a nan gaba.Idan aka yi la'akari da matsalolin toxicological da ke da alaƙa da bayyanar chlormequat a cikin nazarin dabbobi, da kuma yaduwar yawan jama'a ga chlormequat a cikin ƙasashen Turai (kuma a yanzu yana yiwuwa a Amurka), tare da cututtukan cututtuka da na dabbobi, akwai buƙatar gaggawa Kula da chlormequat a cikin abinci da mutane Chlormequat.Yana da mahimmanci a fahimci yuwuwar haɗarin kiwon lafiya na wannan sinadari na aikin gona a matakan bayyanar da muhalli, musamman lokacin daukar ciki.
Lokacin aikawa: Mayu-29-2024