Ingantacciyar magungunan dabbobi Colistin Sulfate CAS 1264-72-8

Bayanin Samfura

Yana da tasiri mai ƙarfi mai ƙarfi akan ƙwayoyin gram-korau, kuma ƙwayoyin cuta masu mahimmanci sun haɗa da Pseudomonas aeruginosa, Escherichia coli, Enterobacteria, Klebsiella, Salmonella, Shigella, Pasteurella da Vibrio. Proteus, Brucella, Serratia da duk kwayoyin cutar Gram sun kasance masu juriya ga wannan samfurin.Colistin sulfatedon jinkirin disinfectant, babban rawar da ke cikin membranes na ƙwayoyin cuta, lokacin da ake hulɗa da ƙwayoyin cuta masu mahimmanci, tsarin sinadarai na amino (Yang) da phosphate ester na tushen phosphoric acid akan membrane cell na kwayan cuta (tare da electronegative), ƙara haɓakar membrane. , haifar da tantanin halitta na abubuwa masu mahimmanci irin su amino acid, waƙoƙin Piao, pyrimidine, K + daga ciki.

Aaikace-aikace

An fi amfani da shi don magance cututtukan hanji da ke haifar da Grame-negative bacilli (Escherichia coli, da dai sauransu). Hakanan yana da tasiri akan Pseudomonas aeruginosa (sepsis, kamuwa da cutar urinary, ƙonewa ko kamuwa da rauni mai rauni).

Siffofin

(1) Yana da tsananin juriya ga ƙwayoyin cuta na Gram negative. Musamman, yana da takamaiman tasiri na hana ci gaba akan Escherichia coli, Salmonella, da Pseudomonas aeruginosa.

(2) Yana da sakamako na bactericidal. Ta hanyar hana aikin ɓarkewar ƙwayar ƙwayar ƙwayar ƙwayar cuta, ƙwayoyin cuta suna mutuwa.

(3) Kusan babu al'amurran da suka shafi juriya na miyagun ƙwayoyi. Ba a sami juriya ga R-factor ba.

(4) Yana aiki tare tare da magungunan ƙwayoyin cuta na anti gram tabbatacce. Idan aka hada da zinc bacitracin, flavomycin, sulfonamides, penicillin semi roba, gentamicin, da sauransu, tasirin ya fi kyau.

(5) Babu saura. Lokacin da ake gudanar da shi ta baki, kusan ba ya shiga hanji, amma a lokacin allurar intramuscular, tarin jini da sha yana da kyau, don haka babu buƙatar damuwa game da ragowar kayan dabba.

(6) Samar da ci gaban kiwo da kiwon kaji, da yin rigakafin kamuwa da cututtuka masu yaduwa a cikin dabbobi da kiwo.